LIST OF PHD TOPICS FOR 2025 (PhD starting Sept 2025, or exceptional cases in January - see below)
POST-DOC POSITIONS OPENED (apply ASAP, start negotiable)
LAB TECHNICIAN-POSITION OPENED (apply ASAP, start negotiable)

VIDEO TOUR THROUGH OUR LAB AND FACILITIES

HOW TO APPLY:
* To apply please contact the supervisor and submit a CV by email to: marek.mraz@email.cz
* The PhD students: APPLY before 1st Feb 2025 to start Sept 2025 (we also in special cases accept student starting from January 2025, and they need to apply by end of Sept 2024), international and czech students are accepted for CEITEC PhD school , or czech students for a PhD program at Faculty of Medicine
* The post-doc positions are opened for enrolment (start of position is negotiable). APPLY AS SOON AS POSSIBLE!

WHAT DO WE OFFER:
* modern laboratories, high risk and high gain projects, state-of-the-art instrumentation
* competitive scholarship + salary for PhD student (minimal guaranteed net income) and a full contract for Post-Docs with competitive salary
* You will work in a team of young investigators that challenge major problems in the field of hematology. We do basic and translational science, but with the objective to help patients in the future (we have access to primary samples with hem. malignancies, and we suggest novel clinical trials).

WHAT WILL YOU LEARN/DO:
* How to think and work independently as a scientist, design experiments and formulate hypothesis
* Writing of abstracts and papers (and course in grant writing and presentation of data)
* How to present data and will attend conferences to present your research
* You will spend 1-2 months visit(s) in collaborating labs in Europe or US
* Collaboration with experts in wet lab research and bioinformatics
* How to critically analyze scientific data (regular journal clubs)
* Classical and novel methods of molecular biology (e.g. RNAseq, Crispr, Cut&Tag, mouse mdoels, immunoblotting, flow cytometry, qRT-PCR, cell cultures, cloning), and you will use our in vitro models for microenvironmental interactions, and artificial activation/inhibition signalling pathways to decipher the gene regulatory loops.
* You can supervise students if interested

WHO ARE WE LOOKING FOR:
* Motivated smart people that have the "drive" to work independently, but also willing to learn from other people in the lab and collaborate.
* Candidates should have a degree in Molecular biology, Biochemistry, or similar field and have deep interest in molecular biology and cancer cell biology.


OTHER INFO:

Brno is among the top 5 cities to live in for students: The research is funded by ERC grant, and will be conducted at CEITEC MASARYK UNIVERSITY (campus Bohunice). Our laboratory extensively collaborates with the University Hospital Brno in the same campus to obtain primary samples from patients. The campus provides a vibrant, multidisciplinary and highly collaborative scientific environment. The lab is located in Brno, the second-largest city in Czech Republic that has the biggest concentration of biomedical research in the region. Brno is one of the major cultural hubs, with a vibrant and lively atmosphere housing ~60.000 students. The city has a very good public transport and plenty of interesting places to visit within the reach of trains (within small distance of several major cities such as Prague, Vienna, Bratislava, Budapest) and close to international airports.

RESEARCH FUNDED BY ERC Starting Grant, EHA, Czech Science Foundation, and Ministry of Health of the Czech Rep.